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Article

Allergic rhinitis and polymorphisms of the interleukin 1 gene complex.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology - 1 Sept 2003

Joki-Erkkilä Veli-Pekka, Karjalainen Jussi, Hulkkonen Janne, Pessi Tanja, Nieminen Markku M, Aromaa Arpo, Klaukka Timo, Hurme Mikko

Abstract excerpt

BACKGROUND: Allergic rhinitis is a chronic inflammatory disease with a genetic background. Inflammatory reactions are regulated by cytokines. Cytokine genes are polymorphic and have been implicated as candidate genes in allergy. OBJECTIVES: To study the significance of the interleukin 1 (IL-1) gene complex in allergic rhinitis. METHODS: Population-based, cross-sectional study. We studied the polymorphisms of 3...

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PMID: 14533660
DOI: 10.1016/S1081-1206(10)63530-2

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