Article
Association study of the interleukin-1 gene complex and tumor necrosis factor alpha gene with suicide attempts.
Psychiatric genetics - 1 Jun 2008
Sáiz Pilar A, García-Portilla Paz, Paredes Begoña, Arango Celso, Morales Blanca, Alvarez Victoria, Coto Eliécer, Bascarán María-Teresa, Bousoño Manuel, Bobes Julio
Abstract excerpt
To investigate the association between four functional polymorphisms in interleukin-1 (IL-1) [IL-1 alpha -889 C/T, IL-1 beta +3953 C/T, IL-1RA (86 bp)n] and tumor necrosis factor alpha (TNFalpha) (-308A/G) genes and suicide attempts. Distribution of the aforesaid polymorphisms was analyzed in 193 suicide attempters compared with 420 unrelated healthy controls from Asturias (Northern Spain). Genotypes were...
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