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Article

Modelling and imaging cardiac repolarization abnormalities.

Journal of internal medicine - 1 Jan 2006

Rudy Y

Abstract excerpt

Repolarization abnormalities, including those induced by the congenital or acquired long QT (LQT) syndrome, provide a substrate for life-threatening cardiac arrhythmias. In this article, we use computational biology to link HERG mutations mechanistically to the resulting abnormalities of the whole-cell action potential. We study how the kinetic properties of I(Ks) (the slow delayed rectifier) that are conferred...

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Identifiers

PMID: 16336517
DOI: 10.1111/j.1365-2796.2005.01586.x
PMCID: PMC1865512

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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