Article
From genetics to cellular function using computational biology.
Annals of the New York Academy of Sciences - 1 May 2004
Rudy Yoram
Abstract excerpt
This article illustrates how computational biology (computer modeling) can be used to link genetic mutations to their cellular phenotypes. Examples are provided from ion channel defects that are associated with hereditary cardiac arrhythmias--that is, the long QT and Brugada syndromes. State-spec...
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