Article
Association of the FBXO11 gene with chronic otitis media with effusion and recurrent otitis media: the Minnesota COME/ROM Family Study.
Archives of otolaryngology--head & neck surgery - 1 Jul 2006
Segade Fernando, Daly Kathleen A, Allred Dax, Hicks Pamela J, Cox Miranda, Brown Mark, Hardisty-Hughes Rachel E, Brown Steve D M, Rich Stephen S, Bowden Donald W
Abstract excerpt
OBJECTIVE: The FBXO11 gene is the human homologue of the gene mutated in the novel deaf mouse mutant jeff (Jf), a single gene model of otitis media. We have evaluated single nucleotide polymorphisms (SNPs) in the FBXO11 gene for association with chronic otitis media with effusion/recurrent otitis media (COME/ROM). DESIGN: A total of 13 SNPs were genotyped across the 98.7 kilobases of genomic DNA encompassing...
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