Article
Significant linkage at chromosome 19q for otitis media with effusion and/or recurrent otitis media (COME/ROM).
BMC medical genetics - 26 Sept 2011
Chen Wei-Min, Allen E Kaitlynn, Mychaleckyj Josyf C, Chen Fang, Hou Xuanlin, Rich Stephen S, Daly Kathleen A, Sale Michèle M
Abstract excerpt
BACKGROUND: In previous analyses, we identified a region of chromosome 19 as harboring a susceptibility locus for chronic otitis media with effusion and/or recurrent otitis media (COME/ROM). Our aim was to further localize the linkage signal and ultimately identify the causative variant or variants. We followed up our previous linkage scan with dense SNP genotyping across in a 5 Mb region. A total of 607...
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