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Article

Evaluation of 15 functional candidate genes for association with chronic otitis media with effusion and/or recurrent otitis media (COME/ROM).

PloS one - 1 Jan 2011

Sale Michèle M, Chen Wei-Min, Weeks Daniel E, Mychaleckyj Josyf C, Hou Xuanlin, Marion Miranda, Segade Fernando, Casselbrant Margaretha L, Mandel Ellen M, Ferrell Robert E, Rich Stephen S, Daly Kathleen A

Abstract excerpt

DNA sequence variants in genes involved in the innate immune response and secondary response to infection may confer susceptibility to chronic otitis media with effusion and/or recurrent otitis media (COME/ROM). We evaluated single nucleotide polymorphisms (SNPs) in 15 functional candidate genes. A total of 99 SNPs were successfully genotyped on the Sequenom platform in 142 families (618 subjects) from the...

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Identifiers

PMID: 21857919
DOI: 10.1371/journal.pone.0022297
PMCID: PMC3156706

Genes

SFTPD
TLR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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