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Article

Direct transduction of allele-specific primer extension into electrical signal using genetic field effect transistor.

Biosensors & bioelectronics - 15 Feb 2007

Sakata Toshiya, Miyahara Yuji

Abstract excerpt

We have developed a genetic field effect transistor (FET) for single nucleotide polymorphism (SNP) genotyping, which is based on potentiometric detection of molecular recognition on the gate insulator. Here, we report direct transduction of allele-specific primer extension on the gate surface into electrical signal using the genetic FETs. This method is based on detection of intrinsic negative charges of...

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PMID: 16844364
DOI: 10.1016/j.bios.2006.05.031

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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