Article
Electrical Detection Assay Based on Programmable Nucleic Acid Probe for Efficient Single-Nucleotide Polymorphism Identification.
ACS sensors - 26 May 2023
Zhang Yun, Chen Bo, Chen Duo, Wang Yiming, Lu Qingqing, Tan Jie, Chen Long, Zhou Liping, Tan Weihong, Yang Yanbing, Yuan Quan
Abstract excerpt
The large-scale pandemic and fast evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have triggered an urgent need for an efficient and sensitive on-site nucleic acid testing method with single-nucleotide polymorphism (SNP) identification capability. Here, we report a multiplexed electrical detection assay based on a paperclip-shaped nucleic acid probe (PNprobe) functionalized...
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