Article
Label-free detection of single nucleotide polymorphisms utilizing the differential transfer function of field-effect transistors.
Biosensors & bioelectronics - 15 Jun 2007
Ingebrandt S, Han Y, Nakamura F, Poghossian A, Schöning M J, Offenhäusser A
Abstract excerpt
We present a label-free method for the detection of DNA hybridization, which is monitored by non-metallized silicon field-effect transistors (FET) in a microarray approach. The described method enables a fast and fully electronic readout of ex situ binding assays. The label-free detection utilizing the field-effect is based on the intrinsic charge of the DNA molecules and/or on changes of the solid-liquid...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
