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Article

Single nucleotide polymorphism analysis by chip-based hybridization and direct current electrical detection of gold-labeled DNA.

Analytical and bioanalytical chemistry - 1 Jun 2004

Burmeister Jens, Bazilyanska Viktoria, Grothe Klaus, Koehler Burkhard, Dorn Ingmar, Warner Brian D, Diessel Edgar

Abstract excerpt

Single nucleotide polymorphism (SNP) analysis at the point of care requires a low cost detection technology that is capable of miniaturization, multiplexing, and high sensitivity. Direct current electrical detection (DCED) of DNA following nanoparticle labeling and silver enhancement is a promising candidate technology for point-of-care diagnostics. In this work we present, for the first time, SNP analysis in PCR...

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PMID: 15057502
DOI: 10.1007/s00216-004-2601-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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