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Article

Detection of single-nucleotide polymorphisms based on the formation of an electron-transfer impeding layer on an electrode surface.

Chemical communications (Cambridge, England) - 14 Jan 2013

Gao Zhiqiang, Shen Wei, Deng Huimin, Ren Yuqian

Abstract excerpt

An electrochemical biosensor utilizing the electron-transfer impeding (insulating) power of a conducting polymer for label-free genotyping single-nucleotide polymorphisms is proposed. Excellent selectivity and sensitivity are accomplished through the engagement of a nuclease clean-up step and a cumulative signal generation/amplification process, respectively.

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PMID: 23187763
DOI: 10.1039/c2cc37450a

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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