Article
Comparison of SNP tagging methods using empirical data: association study of 713 SNPs on chromosome 12q14.3-12q24.21 for asthma and total serum IgE in an African Caribbean population.
Genetic epidemiology - 1 Nov 2006
Chi Peter B, Duggal Priya, Kao W H Linda, Mathias Rasika A, Grant Audrey V, Stockton Maria L, Garcia Joe G N, Ingersoll Roxann G, Scott Alan F, Beaty Terri H, Barnes Kathleen C, Fallin M Daniele
Abstract excerpt
Few comparison studies have been performed on single nucleotide polymorphism (SNP) tagging methods to examine their consistency and effectiveness in terms of inferences about association with disease. We applied several SNP tagging methods to SNPs on chromosome 12q (n=713) and compared the utility of these methods to detect association for asthma and serum IgE levels among a sample of African Caribbean families...
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