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Article

Resequencing candidate genes implicates rare variants in asthma susceptibility.

American journal of human genetics - 10 Feb 2012

Torgerson Dara G, Capurso Daniel, Mathias Rasika A, Graves Penelope E, Hernandez Ryan D, Beaty Terri H, Bleecker Eugene R, Raby Benjamin A, Meyers Deborah A, Barnes Kathleen C, Weiss Scott T, Martinez Fernando D, Nicolae Dan L, Ober Carole

Abstract excerpt

Common variation in over 100 genes has been implicated in the risk of developing asthma, but the contribution of rare variants to asthma susceptibility remains largely unexplored. We selected nine genes that showed the strongest signatures of weak purifying selection from among 53 candidate asthma-associated genes, and we sequenced the coding exons and flanking noncoding regions in 450 asthmatic cases and 515...

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Identifiers

PMID: 22325360
DOI: 10.1016/j.ajhg.2012.01.008
PMCID: PMC3276672

Genes

DPP10
AGT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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