Article
Genome-wide search for asthma susceptibility loci in a founder population. The Collaborative Study on the Genetics of Asthma.
Human molecular genetics - 1 Sept 1998
Ober C, Cox N J, Abney M, Di Rienzo A, Lander E S, Changyaleket B, Gidley H, Kurtz B, Lee J, Nance M, Pettersson A, Prescott J, Richardson A, Schlenker E, Summerhill E, Willadsen S, Parry R
Abstract excerpt
Founder populations offer many advantages for mapping genetic traits, particularly complex traits that are likely to be genetically heterogeneous. To identify genes that influence asthma and asthma-associated phenotypes, we conducted a genome-wide screen in the Hutterites, a religious isolate of...
Topics
- Adolescent
- Adult
- Alleles
- Asthma
- Bronchial Hyperreactivity
- Child, Preschool
- Chromosome Mapping
- Consanguinity
- Female
- Founder Effect
- Genetic Linkage
- Genetic Markers
- Genetic Testing
- Genome, Human