Article
A genome-wide association study on African-ancestry populations for asthma.
The Journal of allergy and clinical immunology - 1 Feb 2010
Mathias Rasika A, Grant Audrey V, Rafaels Nicholas, Hand Tracey, Gao Li, Vergara Candelaria, Tsai Yuhjung J, Yang Mao, Campbell Monica, Foster Cassandra, Gao Peisong, Togias A, Hansel Nadia N, Diette Gregory, Adkinson N Franklin, Liu Mark C, Faruque Mezbah, Dunston Georgia M, Watson Harold R, Bracken Michael B, Hoh Josephine, Maul Pissamai, Maul Trevor, Jedlicka Anne E, Murray Tanda, Hetmanski Jacqueline B, Ashworth Roxann, Ongaco Chrissie M, Hetrick Kurt N, Doheny Kimberly F, Pugh Elizabeth W, Rotimi Charles N, Ford Jean, Eng Celeste, Burchard Esteban G, Sleiman Patrick M A, Hakonarson Hakon, Forno Erick, Raby Benjamin A, Weiss Scott T, Scott Alan F, Kabesch Michael, Liang Liming, Abecasis Gonçalo, Moffatt Miriam F, Cookson William O C, Ruczinski Ingo, Beaty Terri H, Barnes Kathleen C
Abstract excerpt
BACKGROUND: Asthma is a complex disease characterized by striking ethnic disparities not explained entirely by environmental, social, cultural, or economic factors. Of the limited genetic studies performed on populations of African descent, notable differences in susceptibility allele frequencies have been observed. OBJECTIVES: We sought to test the hypothesis that some genes might contribute to the profound...
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