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Article

Negative Regulation of the RelA/p65 Transactivation Function by the Product of the DEK Proto-oncogene

8 Jul 2006

Abstract excerpt

NF-kappaB-mediated transcriptional activation is controlled at several levels including interaction with coregulatory proteins. To identify new proteins capable of modulating NF-kappaB-mediated activation, a cytoplasmic two-hybrid screen was performed using the p65 C-terminal transactivation domain as bait and identified the product of the DEK proto-oncogene. DEK is a ubiquitous nuclear protein that has been...

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PMID: 16829531
DOI: 10.1074/jbc.m600915200

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