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Article

Deposition of mouse amyloid beta in human APP/PS1 double and single AD model transgenic mice.

Neurobiology of disease - 1 Sept 2006

van Groen Thomas, Kiliaan Amanda J, Kadish Inga

Abstract excerpt

The deposition of amyloid beta (Abeta) peptides and neurofibrillary tangles are the two characteristic pathological features of Alzheimer's disease (AD). To investigate the relation between amyloid precursor protein (APP) production, amyloid beta deposition and the type of Abeta in deposits, i.e., human and/or mouse, we performed a histopathological analysis, using mouse and human specific antibodies, of the...

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Source

Identifiers

PMID: 16829076
DOI: 10.1016/j.nbd.2006.05.010

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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