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Article

Cerebrovascular phenotypes in mouse models of Alzheimer's disease.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism - 1 Aug 2021

Szu Jenny I, Obenaus André

Abstract excerpt

Alzheimer's disease (AD) is a devastating neurological degenerative disorder and is the most common cause of dementia in the elderly. Clinically, AD manifests with memory and cognitive decline associated with deposition of hallmark amyloid beta (Aβ) plaques and neurofibrillary tangles (NFTs). Although the mechanisms underlying AD remains unclear, two hypotheses have been proposed. The established amyloid...

Topics

Alzheimer Disease
Amyloid beta-Peptides
Animals
Cerebral Amyloid Angiopathy
Cerebrovascular Circulation
Disease Models, Animal
Mice, Transgenic
Neurofibrillary Tangles
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33557692
DOI: 10.1177/0271678X21992462
PMCID: PMC8327123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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