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Article

P-Glycoprotein Expression as a Predictor of the Outcome of Therapy for Neuroblastoma

5 Dec 1991

Abstract excerpt

BACKGROUND AND METHODS: Multidrug resistance in chemotherapy for cancer is characterized by increased genetic expression of P-glycoprotein, which acts as an ATP-dependent drug-efflux pump. To determine whether P-glycoprotein levels are of prognostic value in such cases, we measured these levels immunohistochemically in a retrospective study of sequential tumor samples from 67 children with neuroblastoma. RESULTS:...

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Identifiers

PMID: 1682809
DOI: 10.1056/nejm199112053252304

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Source receipt: pubmed, retrieved 7 Sept 2026.

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P-Glycoprotein Expression as a Predictor of the Outcome of Therapy for NeuroblastomaPMID 1682809Read ↗

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