Article
The zebrafish mutant vps18 as a model for vesicle-traffic related hypopigmentation diseases.
Pigment cell research - 1 Aug 2006
Maldonado Ernesto, Hernandez Fabiola, Lozano Carlos, Castro Marta E, Navarro Rosa E
Abstract excerpt
Hypopigmentation is a characteristic of several diseases associated with vesicle traffic defects, like the Hermansky-Pudlak, Chediak-Higashi, and Griscelli syndromes. Hypopigmentation is also a characteristic of the zebrafish mutant vps18(hi2499A), which is affected in the gene vps18, a component of the homotypic fusion and protein sorting complex that is involved in tethering during vesicular traffic. Vps18, as...
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