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Article

Murine Hermansky-Pudlak syndrome genes: regulators of lysosome-related organelles.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Jun 2004

Li Wei, Rusiniak Michael E, Chintala Sreenivasulu, Gautam Rashi, Novak Edward K, Swank Richard T

Abstract excerpt

In the mouse, at least 16 genes regulate vesicle trafficking to specialized lysosome-related organelles, including platelet dense granules and melanosomes. Fourteen of these genes have been identified by positional cloning. All 16 mouse mutants are models for the genetically heterogeneous human disease, Hermansky-Pudlak Syndrome (HPS). Five HPS genes encode known vesicle trafficking proteins. Nine genes are...

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Identifiers

PMID: 15170859
DOI: 10.1002/bies.20042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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