Dictyostelium mutants lacking multiple classic myosin I isoforms reveal combinations of shared and distinct functions.

Abstract excerpt

Dictyostelium cells that lack the myoB isoform were previously shown to exhibit reduced efficiencies of phagocytosis and chemotactic aggregation ("streaming") and to crawl at about half the speed of wild-type cells. Of the four other Dictyostelium myosin I isoforms identified to date, myoC and myoD are the most similar to myoB in terms of tail domain sequence. Furthermore, we show here that myoC, like myoB and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antibody Specificity
• Share to Cell Movement
• Share to Dictyostelium