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Article

Alternative lengthening of telomeres in the human adrenocortical carcinoma cell line H295R.

International journal of oncology - 1 Aug 2006

Fujiwara Masachika, Kamma Hiroshi, Wu Wenwen, Yano Yukiko, Homma Shinsuke, Satoh Hiroaki

Abstract excerpt

Telomere maintenance can occur in the absence of telomerase by a mechanism referred to as alternative lengthening of telomeres (ALT). ALT is considered to be rare in tumors of epithelial origin. The biological significance and molecular mechanism of ALT have not been well studied in human cancers. It has been reported that clinical samples of adrenocortical carcinoma show a low incidence of telomerase positivity....

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Identifiers

PMID: 16820888

Genes

PML

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Alternative lengthening of telomeres in the human adrenocortical carcinoma cell line H295R.PMID 16820888Read ↗

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Alternative Lengthening of Telomeres in Human CellsSemantic proximity Read ↗

Pan-Cancer Analysis of Clinical Relevance via Telomere Maintenance MechanismSemantic proximity Read ↗

ALT-associated PML bodies are present in viable cells and are enriched in cells in the G2/M phase of the cell cycleSemantic proximity Read ↗

ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific mannerSemantic proximity Read ↗

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