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Article

Alternative lengthening of telomeres in mammalian cells.

Oncogene - 21 Jan 2002

Henson Jeremy D, Neumann Axel A, Yeager Thomas R, Reddel Roger R

Abstract excerpt

Some immortalized mammalian cell lines and tumors maintain or increase the overall length of their telomeres in the absence of telomerase activity by one or more mechanisms referred to as alternative lengthening of telomeres (ALT). Characteristics of human ALT cells include great heterogeneity of telomere size (ranging from undetectable to abnormally long) within individual cells, and ALT-associated PML bodies...

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Identifiers

PMID: 11850785
DOI: 10.1038/sj.onc.1205058

Genes

PML

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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