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Article

Gene variants of brain dopamine pathways and smoking-induced dopamine release in the ventral caudate/nucleus accumbens.

Archives of general psychiatry - 1 Jul 2006

Brody Arthur L, Mandelkern Mark A, Olmstead Richard E, Scheibal David, Hahn Emily, Shiraga Sharon, Zamora-Paja Eleanor, Farahi Judah, Saxena Sanjaya, London Edythe D, McCracken James T

Abstract excerpt

CONTEXT: Preclinical studies demonstrate that nicotine administration leads to dopamine release in the ventral striatum. However, human studies reveal considerable interindividual variability in the extent of smoking-induced dopamine release. OBJECTIVE: To determine whether common gene variants of the brain dopamine pathway explain this observed phenotypic variability in humans. DESIGN: Blood samples were drawn...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16818870
DOI: 10.1001/archpsyc.63.7.808
PMCID: PMC2873693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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