Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nicotine-specific and non-specific effects of cigarette smoking on endogenous opioid mechanisms.

Progress in neuro-psychopharmacology & biological psychiatry - 1 Aug 2016

Nuechterlein Emily B, Ni Lisong, Domino Edward F, Zubieta Jon-Kar

Abstract excerpt

This study investigates differences in μ-opioid receptor mediated neurotransmission in healthy controls and overnight-abstinent smokers, and potential effects of the OPRM1 A118G genotype. It also examines the effects of smoking denicotinized (DN) and average nicotine (N) cigarettes on the μ-opioid system. Positron emission tomography with (11)C-carfentanil was used to determine regional brain μ-opioid receptor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analgesics, Opioid
Share to Brain Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carbon Radioisotopes

Share to Fentanyl

Share to Nicotine

Share to Nicotinic Agonists

Share to Radiopharmaceuticals

Share to Receptors, Opioid, mu

Source

Open in PubMed Open full text

Identifiers

PMID: 27095017
DOI: 10.1016/j.pnpbp.2016.04.006
PMCID: PMC4891463

Genes

OPRM1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nicotine-specific and non-specific effects of cigarette smoking on endogenous opioid mechanisms.PMID 27095017Read ↗

Regional brain [(11)C]carfentanil binding following tobacco smoking.Semantic proximity Read ↗

Human Mu Opioid Receptor (OPRM1 A118G) polymorphism is associated with brain mu-opioid receptor binding potential in smokers.Semantic proximity Read ↗

Tobacco smoking produces greater striatal dopamine release in G-allele carriers with mu opioid receptor A118G polymorphism.Semantic proximity Read ↗

Clinical pharmacology of nicotine: implications for understanding, preventing, and treating tobacco addiction.Semantic proximity Read ↗

Impact of genetic variability in nicotinic acetylcholine receptors on nicotine addiction and smoking cessation treatment.Semantic proximity Read ↗

Influence of the A118G Polymorphism of the OPRM1 Gene and Exon 3 VNTR Polymorphism of the DRD4 Gene on Cigarette Craving After Alcohol Administration.Semantic proximity Read ↗

Nicotinic receptors in the medial habenula to interpeduncular nucleus pathway: modulators of reward, aversion and emotionSemantic proximity Read ↗

Interacting effects of naltrexone and OPRM1 and DAT1 variation on the neural response to alcohol cues.Semantic proximity Read ↗

Effects of nicotine deprivation and replacement on BOLD-fMRI response to smoking cues as a function of DRD4 VNTR genotype.Semantic proximity Read ↗

The galanin receptor 1 gene associates with tobacco craving in smokers seeking cessation treatment.Semantic proximity Read ↗

Current Understanding of the Neurobiology of Opioid Use Disorder: an OverviewSemantic proximity Read ↗

Increased habenular connectivity in opioid users is associated with an α5 subunit nicotinic receptor genetic variant.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.