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Article

Familial Analysis of Epistatic and Sex-Dependent Association of Genes of the Renin-Angiotensin-Aldosterone System and Blood Pressure.

Circulation. Cardiovascular genetics - 1 Jun 2017

Scurrah Katrina J, Lamantia Angela, Ellis Justine A, Harrap Stephen B

Abstract excerpt

BACKGROUND: Renin-angiotensin-aldosterone system genes have been inconsistently associated with blood pressure, possibly because of unrecognized influences of sex-dependent genetic effects or gene-gene interactions (epistasis). METHODS AND RESULTS: We tested association of systolic blood pressure with single-nucleotide polymorphisms (SNPs) at renin (REN), angiotensinogen (AGT), angiotensin-converting enzyme...

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Share to Angiotensinogen
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 CYP11B2

Share to Epistasis, Genetic

Share to Peptidyl-Dipeptidase A

Share to Receptor, Angiotensin, Type 1

Share to Renin-Angiotensin System

Source

Identifiers

PMID: 28506960
DOI: 10.1161/CIRCGENETICS.116.001595

Genes

ACE
AGT
AGTR1
REN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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