Article
Effects of polymorphisms in ERCC1, ASE-1 and RAI on the risk of colorectal carcinomas and adenomas: a case control study.
BMC cancer - 3 Jul 2006
Skjelbred Camilla F, Saebø Mona, Nexø Bjørn A, Wallin Håkan, Hansteen Inger-Lise, Vogel Ulla, Kure Elin H
Abstract excerpt
BACKGROUND: The risk of sporadic colorectal cancer is mainly associated with lifestyle factors and may be modulated by several genetic factors of low penetrance. Genetic variants represented by single nucleotide polymorphisms in genes encoding key players in the adenoma carcinoma sequence may contribute to variation in susceptibility to colorectal cancer. In this study, we aimed to evaluate whether the recently...
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