Article
Polymorphisms of the XRCC1, XRCC3 and XPD genes and risk of colorectal adenoma and carcinoma, in a Norwegian cohort: a case control study.
BMC cancer - 16 Mar 2006
Skjelbred Camilla Furu, Saebø Mona, Wallin Håkan, Nexø Bjørn Andersen, Hagen Per Christian, Lothe Inger Marie Bowitz, Aase Steinar, Johnson Egil, Hansteen Inger-Lise, Vogel Ulla, Kure Elin H
Abstract excerpt
BACKGROUND: Genetic polymorphisms in DNA repair genes may influence individual variation in DNA repair capacity, which may be associated with risk of developing cancer. For colorectal cancer the importance of mutations in mismatch repair genes has been extensively documented. Less is known about other DNA repair pathways in colorectal carcinogenesis. In this study we have focused on the XRCC1, XRCC3 and XPD...
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