Article
Vitamin D Receptor Polymorphisms Relate to Risk of Adenomatous Polyps in a Sex-Specific Manner.
Nutrition and cancer - 1 Jan 2016
Beckett Emma Louise, Le Gras Kathleen, Martin Charlotte, Boyd Lyndell, Ng Xiaowei, Duesing Konsta, Yates Zoe, Veysey Martin, Lucock Mark
Abstract excerpt
Vitamin D receptor (VDR) gene polymorphisms may influence risk for adenomatous polyps (AP), a benign precursor to colon cancer, via modulation of vitamin D sensitive pathways, including cell proliferation and differentiation. However, results have been mixed and any association remains contentious. Failure to clinically exclude the presence of (AP in control cohorts may contribute to the lack of consensus....
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