Article
Polymorphisms in the interleukin-6 receptor gene are associated with body mass index and with characteristics of the metabolic syndrome.
Clinical endocrinology - 1 Jul 2006
Esteve Eduardo, Villuendas Gemma, Mallolas Judith, Vendrell Joan, López-Bermejo Abel, Rodríguez Matilde, Recasens Mónica, Ricart Wifredo, San Millán José L, Escobar-Morreale Héctor, Richart Cristóbal, Fernández-Real José Manuel
Abstract excerpt
OBJECTIVE: Low-grade inflammation has been related to obesity, insulin resistance and the metabolic syndrome. The Asp358Ala variant and the CA-repeat polymorphism in the interleukin-6 receptor (IL-6R) gene have been reported to be associated with obesity in Pima Indians and Spanish women, respectively. The aim of this study was to investigate the association between these polymorphisms and obesity in a...
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