Article
Polymorphisms in the interleukin-6 receptor gene (Asp358Ala) and body mass index in Chilean women with type 1 diabetes.
Endocrine research - 1 Jan 2012
Pérez-Bravo Francisco, Oyarzún Ana María, Soto Francisca, López Patricia, Eyzaguirre Francisca, Codner Ethel
Abstract excerpt
INTRODUCTION: Interleukin-6 receptor (IL6R) has been linked with type 2 diabetes and obesity. The presence of the Asp allele in Asp358Ala of IL6R has been linked with insulin resistance and weight gain. AIM: The aim of this study is to evaluate the frequency and the association of the Asp358Ala in the IL6R gene in Chilean women with type 1 diabetes (T1D) and its relationship with body mass index (BMI). PATIENTS...
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