Article
Interleukin-6 promoter polymorphism and cardiovascular risk factors: the Health 2000 Survey.
Atherosclerosis - 1 Dec 2009
Riikola Antti, Sipilä Kalle, Kähönen Mika, Jula Antti, Nieminen Markku S, Moilanen Leena, Kesäniemi Y Antero, Lehtimäki Terho, Hulkkonen Janne
Abstract excerpt
OBJECTIVE: Inflammatory factors modify the risk of cardiovascular diseases and atherosclerosis. The single base genetic polymorphism in the promoter region of inflammatory cytokine interleukin-6 (IL6 -174 G>C, rs1800795) is associated with the variation of IL-6 production. The aim of this study was to investigate whether IL6 -174 G>C is associated with the risk factors and early markers of atherosclerosis....
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