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Article

Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes.

Diabetologia - 1 Feb 2005

Hamid Y H, Rose C S, Urhammer S A, Glümer C, Nolsøe R, Kristiansen O P, Mandrup-Poulsen T, Borch-Johnsen K, Jorgensen T, Hansen T, Pedersen O

Abstract excerpt

AIMS/HYPOTHESIS: The cytokine interleukin 6 (IL-6) is an essential regulator of the acute phase response associated with insulin-resistant states including type 2 diabetes and obesity. Three polymorphisms at positions -597, -572, and -174 of the IL6 promoter have been reported to influence IL6 transcription. The aim of this study was to investigate whether the IL6 promoter polymorphisms were associated with...

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PMID: 15645209
DOI: 10.1007/s00125-004-1623-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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