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Article

Variation in the interleukin-6 receptor gene associates with type 2 diabetes in Danish whites.

Diabetes - 1 Dec 2004

Hamid Yasmin H, Urhammer Søren A, Jensen Dorit P, Glümer Charlotte, Borch-Johnsen Knut, Jørgensen Torben, Hansen Torben, Pedersen Oluf

Abstract excerpt

Interleukin-6 (IL-6) is a pleiotropic cytokine involved in the pathophysiology of various human diseases such as type 2 diabetes and obesity. IL-6 signals via a heterodimeric receptor complex consisting of a soluble IL-6 alpha-subunit (IL-6 receptor [IL6R]) and a signal transducing subunit (gp130). The IL6R gene maps to an important candidate locus for type 2 diabetes on chromosome 1q21. An Asp358Ala polymorphism...

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Identifiers

PMID: 15561970
DOI: 10.2337/diabetes.53.12.3342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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