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Article

HIV-1 subtype C viruses rapidly develop K65R resistance to tenofovir in cell culture.

AIDS (London, England) - 12 Jun 2006

Brenner Bluma G, Oliveira Maureen, Doualla-Bell Florence, Moisi Daniela D, Ntemgwa Michel, Frankel Fernando, Essex Max, Wainberg Mark A

Abstract excerpt

BACKGROUND: Genotypic diversity among HIV-1 subtypes and circulating recombinant forms (CRF) may lead to distinct pathways to drug resistance. This study evaluated subtype-related differences in the development of resistance in culture to tenofovir. METHODS: Genotyping determined nucleotide diversity among subtypes. Representative subtype B, C, CRF1_AE, CRF2_AG, G, and HIV-2 isolates were selected for resistance...

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Source

Identifiers

PMID: 16816549
DOI: 10.1097/01.aids.0000232228.88511.0b

Genes

AGA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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