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Article

Nucleic acid template and the risk of a PCR-Induced HIV-1 drug resistance mutation.

PloS one - 7 Jun 2010

Varghese Vici, Wang Elijah, Babrzadeh Farbod, Bachmann Michael H, Shahriar Rajin, Liu Tommy, Mappala Svetlana Jean M, Gharizadeh Baback, Fessel W Jeffrey, Katzenstein David, Kassaye Seble, Shafer Robert W

Abstract excerpt

BACKGROUND: The HIV-1 nucleoside RT inhibitor (NRTI)-resistance mutation, K65R confers intermediate to high-level resistance to the NRTIs abacavir, didanosine, emtricitabine, lamivudine, and tenofovir; and low-level resistance to stavudine. Several lines of evidence suggest that K65R is more comm...

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Identifiers

PMID: 20539818
DOI: 10.1371/journal.pone.0010992
PMCID: PMC2881873

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20539818-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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