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Article

Prevalence of the K65R resistance reverse transcriptase mutation in different HIV-1 subtypes in Israel.

Journal of medical virology - 1 Sept 2009

Turner Dan, Shahar Eduardo, Katchman Eugene, Kedem Eynat, Matus Natasha, Katzir Michal, Hassoun Gamal, Pollack Shimon, Kessner Rivka, Wainberg Mark A, Avidor Boaz

Abstract excerpt

The K65R mutation in HIV-1 reverse transcriptase (RT) can be selected by the RT inhibitors tenofovir (TDF), abacavir (ABC), and didanosine (DDI). Recently, in vitro studies have shown that K65R is selected in tissue culture more rapidly with subtype C than subtype B viruses. The prevalence of K65R in viruses sequenced at the Tel-Aviv AIDS Center was evaluated. This study analyzed retrospectively sequences from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19626612
DOI: 10.1002/jmv.21567

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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