Article
High rate of K65R for antiretroviral therapy-naive patients with subtype C HIV infection failing a tenofovir-containing first-line regimen.
AIDS (London, England) - 24 Aug 2012
Sunpath Henry, Wu Baohua, Gordon Michelle, Hampton Jane, Johnson Brent, Moosa Mahomed-Yunus S, Ordonez Claudia, Kuritzkes Daniel R, Marconi Vincent C
Abstract excerpt
OBJECTIVE: We sought to determine the rate of the K65R mutation in patients receiving tenofovir (TDF)-based antiretroviral therapy (ART) with subtype C HIV infection. DESIGN: Retrospective cohort study. METHODS: All patients initiated on stavudine (d4T) with lamivudine (3TC) or TDF with 3TC and a nonnucleoside reverse transcriptase inhibitor at McCord Hospital in Durban, South Africa had their charts reviewed....
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