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Article

An association between K65R and HIV-1 subtype C viruses in patients treated with multiple NRTIs.

The Journal of antimicrobial chemotherapy - 1 Jul 2017

Smit Erasmus, White Ellen, Clark Duncan, Churchill Duncan, Zhang Hongyi, Collins Simon, Pillay Deenan, Sabin Caroline, Nelson Mark, Winston Alan, Jose Sophie, Tostevin Anna, Dunn David T

Abstract excerpt

Objectives: HIV-1 subtype C might have a greater propensity to develop K65R mutations in patients with virological failure compared with other subtypes. However, the strong association between viral subtype and confounding factors such as exposure groups and ethnicity affects the calculation of this propensity. We exploited the diversity of viral subtypes within the UK to undertake a direct comparative analysis....

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Source

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Identifiers

PMID: 28379449
DOI: 10.1093/jac/dkx091
PMCID: PMC5890671

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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