Article
Fractional allelic imbalance in human breast cancer increases with tetraploidization and chromosome loss.
International journal of cancer - 20 Feb 1992
Cornelisse C J, Kuipers-Dijkshoorn N, van Vliet M, Hermans J, Devilee P
Abstract excerpt
We have previously reported a complete allelotype study of 86 primary breast carcinomas, in which each non-acrocentric chromosome arm was studied with at least one polymorphic DNA-marker for the presence of allelic imbalance (AI, allelic loss or allelic gain) in the tumor. Here we report the statistical analysis of this data set, investigating the relationships between AI, DNA aneuploidy and several...
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