Fractional allelic imbalance in human breast cancer increases with tetraploidization and chromosome loss.

doi:10.1002/ijc.2910500408

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Article

Fractional allelic imbalance in human breast cancer increases with tetraploidization and chromosome loss.

International journal of cancer - 20 Feb 1992

Cornelisse C J, Kuipers-Dijkshoorn N, van Vliet M, Hermans J, Devilee P

Abstract excerpt

We have previously reported a complete allelotype study of 86 primary breast carcinomas, in which each non-acrocentric chromosome arm was studied with at least one polymorphic DNA-marker for the presence of allelic imbalance (AI, allelic loss or allelic gain) in the tumor. Here we report the stat...

Topics

Alleles
Aneuploidy
Breast Neoplasms
Cell Division
Chromosome Aberrations
Chromosome Disorders
DNA, Neoplasm
Humans
Karyotyping
Survival Analysis
Time Factors

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