Article
Functional and physical interaction of yeast Mgs1 with PCNA: impact on RAD6-dependent DNA damage tolerance.
Molecular and cellular biology - 1 Jul 2006
Hishida Takashi, Ohya Tomoko, Kubota Yoshino, Kamada Yusuke, Shinagawa Hideo
Abstract excerpt
Proliferating cell nuclear antigen (PCNA), a sliding clamp required for processive DNA synthesis, provides attachment sites for various other proteins that function in DNA replication, DNA repair, cell cycle progression and chromatin assembly. It has been shown that differential posttranslational modifications of PCNA by ubiquitin or SUMO play a pivotal role in controlling the choice of pathway for rescuing...
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