Article
Measuring nanometer scale gradients in spindle microtubule dynamics using model convolution microscopy.
Molecular biology of the cell - 1 Sept 2006
Pearson Chad G, Gardner Melissa K, Paliulis Leocadia V, Salmon E D, Odde David J, Bloom Kerry
Abstract excerpt
A computational model for the budding yeast mitotic spindle predicts a spatial gradient in tubulin turnover that is produced by kinetochore-attached microtubule (kMT) plus-end polymerization and depolymerization dynamics. However, kMTs in yeast are often much shorter than the resolution limit of...
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