Article
Molecular analysis of kinetochore-microtubule attachment in budding yeast.
Cell - 27 Jul 2001
He X, Rines D R, Espelin C W, Sorger P K
Abstract excerpt
The complex series of movements that mediates chromosome segregation during mitosis is dependent on the attachment of microtubules to kinetochores, DNA-protein complexes that assemble on centromeric DNA. We describe the use of live-cell imaging and chromatin immunoprecipitation in S. cerevisiae to identify ten kinetochore subunits, among which are yeast homologs of microtubule binding proteins in animal cells. By...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
