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Article

A variable number of tandem repeats polymorphism influences the transcriptional activity of the neonatal Fc receptor alpha-chain promoter.

Immunology - 1 Sept 2006

Sachs Ulrich J H, Socher Ines, Braeunlich Christian G, Kroll Hartmut, Bein Gregor, Santoso Sentot

Abstract excerpt

The neonatal Fc receptor, FcRn, plays a central role in immunoglobulin G (IgG) transport across placental barriers. Genetic variations of FcRn-dependent transport across the placenta may influence antibody-mediated pathologies of the fetus and the newborn. Sequencing analysis of 20 unrelated individuals demonstrated no missense mutation within the five exons of the FcRn gene. However, a variable number of tandem...

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Share to Histocompatibility Antigens Class I
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoglobulin G

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Share to Receptors, Fc

Share to Statistics, Nonparametric

Share to Tandem Repeat Sequences

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Identifiers

PMID: 16805790
DOI: 10.1111/j.1365-2567.2006.02408.x
PMCID: PMC1782336

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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