Article
No association of FCRN promoter VNTR polymorphism with the rate of maternal-fetal IgG transfer.
Journal of reproductive immunology - 1 Jun 2010
Freiberger T, Ravcuková B, Grodecká L, Kurecová B, Jarkovský J, Bartonková D, Thon V, Litzman J
Abstract excerpt
The neonatal Fc receptor (FcRn) plays a critical role in maternal-fetal IgG transfer. Recently, a functionally active promoter polymorphism in the FCRN gene, represented by variable number of tandem repeats (VNTR), has been described. We analysed 103 single fetal samples and 103 paired maternal and fetal samples collected from umbilical cord blood of full-term neonates born from the 38th to the 41st week of...
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