Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiple Roles for the Major Histocompatibility Complex Class I– Related Receptor FcRn

1 Apr 2000

Abstract excerpt

Multiple functions have recently been identified for the neonatal Fc receptor FcRn. In addition, a human homolog of the rodent forms of FcRn has been identified and characterized. This major histocompatibility complex class I-related receptor plays a role in the passive delivery of immunoglobulin (Ig)Gs from mother to young and the regulation of serum IgG levels. In addition, FcRn expression in tissues such as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glycosylation and Glycoproteins Research
Share to Monoclonal and Polyclonal Antibodies Research
Share to Protein purification and stability

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10837074
DOI: 10.1146/annurev.immunol.18.1.739

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiple Roles for the Major Histocompatibility Complex Class I– Related Receptor FcRnPMID 10837074Read ↗

Regulation of Immune Responses by the Neonatal Fc Receptor and Its Therapeutic ImplicationsSemantic proximity Read ↗

The immunologic functions of the neonatal Fc receptor for IgG.Semantic proximity Read ↗

New functions of the MHC class I-related Fc receptor, FcRnSemantic proximity Read ↗

Identification and function of neonatal Fc receptor in mammary gland of lactating miceSemantic proximity Read ↗

FcRn, but not FcγRs, drives maternal-fetal transplacental transport of human IgG antibodiesSemantic proximity Read ↗

Neonatal Fc receptor (FcRn): a novel target for therapeutic antibodies and antibody engineering.Semantic proximity Read ↗

A major histocompatibility complex class I-like Fc receptor cloned from human placenta: possible role in transfer of immunoglobulin G from mother to fetus.Semantic proximity Read ↗

FcRn, but not FcγRs, drives maternal-fetal transplacental transport of human IgG antibodiesSemantic proximity Read ↗

“Ways in which the neonatal Fc-receptor is involved in autoimmunity”Semantic proximity Read ↗

Cloning and analysis of the gene encoding the human neonatal Fc receptorSemantic proximity Read ↗

The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinitySemantic proximity Read ↗

The MHC class I-related receptor, FcRn, plays an essential role in the maternofetal transfer of gamma-globulin in humans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.