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Article

A common haplotype of the annexin A5 (ANXA5) gene promoter is associated with recurrent pregnancy loss

1 Mar 2007

Abstract excerpt

We sought to verify whether variation in the promoter of the gene encoding placental anticoagulant protein annexin A5 (ANXA5) represents a risk factor for recurrent pregnancy loss (RPL). Sequence analysis of 70 German RPL patients, all known to carry neither factor V Leiden nor a prothrombin mutation, revealed four consecutive nucleotide substitutions in the ANXA5 promoter, which were transmitted as a joint...

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PMID: 17339269
DOI: 10.1093/hmg/ddm017

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

A common haplotype of the annexin A5 (ANXA5) gene promoter is associated with recurrent pregnancy lossPMID 17339269Read ↗

Correlation of single nucleotide polymorphisms in the promoter region of the ANXA5 (annexin A5) gene with recurrent miscarriages in women of Greek origin.Semantic proximity Read ↗

Annexin A5 Promoter Haplotype M2 Is Not a Risk Factor for Recurrent Pregnancy Loss in Northern Europe.Semantic proximity Read ↗

Genetic analysis of ANXA5 haplotype and its effect on recurrent pregnancy loss.Semantic proximity Read ↗

Haplotype M2 in the annexin A5 (ANXA5) gene and the occurrence of obstetric complicationsSemantic proximity Read ↗

Association between ANXA5 haplotypes and the risk of recurrent pregnancy loss.Semantic proximity Read ↗

Further insights into the role of the annexin A5 M2 haplotype as recurrent pregnancy loss factor, assessing timing of miscarriage and partner risk.Semantic proximity Read ↗

Polymorphisms in the annexin A5 gene promoter in Japanese women with recurrent pregnancy loss.Semantic proximity Read ↗

Genotyping analyses for polymorphisms of ANXA5 gene in patients with recurrent pregnancy loss.Semantic proximity Read ↗

Maternal carriers of the ANXA5 M2 haplotype are exposed to a greater risk for placenta-mediated pregnancy complications.Semantic proximity Read ↗

Research progress on ANXA5 in recurrent pregnancy loss.Semantic proximity Read ↗

Investigation of the Annexin A5 M2 haplotype in 500 white European couples who have experienced recurrent spontaneous abortion.Semantic proximity Read ↗

Functional characterization of annexin A5 gene promoter allelic variants.Semantic proximity Read ↗

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