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Article

Decreased transcription of the human FCGR2B gene mediated by the -343 G/C promoter polymorphism and association with systemic lupus erythematosus.

Human genetics - 1 Jul 2005

Blank Marissa C, Stefanescu Radu N, Masuda Emi, Marti Francesc, King Philip D, Redecha Patricia B, Wurzburger Robert J, Peterson Margaret G E, Tanaka Shizuko, Pricop Luminita

Abstract excerpt

The role for inhibitory Fc gamma receptors class IIb (FcgammaRIIb) in the onset, progression and severity of several animal models of autoimmune diseases is well established. By contrast, the pathogenic potential of FcgammaRIIb in human autoimmune diseases remains largely unknown. Here we report...

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Source

Identifiers

PMID: 15895258
DOI: 10.1007/s00439-005-1302-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15895258-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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